- Title
- Sensitivity and specificity of the toe-brachial index for detecting peripheral arterial disease: initial findings
- Creator
- Tehan, Peta; Bray, Alan; Keech, Ruth; Rounsley, Richard; Carruthers, Angela; Chuter, Vivienne Helaine
- Relation
- Journal of Ultrasound in Medicine Vol. 34, Issue 10, p. 1737-1743
- Publisher Link
- http://dx.doi.org/10.7863/ultra.15.14.09071
- Publisher
- American Institute for Ultrasound in Medicine
- Resource Type
- journal article
- Date
- 2015
- Description
- OBJECTIVES: The toe-brachial index (TBI) is an alternative to the ankle-brachial index (ABI) in screening for peripheral arterial disease (PAD); however, there is limited evidence comparing their diagnostic accuracy. This study compared the diagnostic accuracy of the ABI and TBI in a population at risk of PAD. METHODS: The sensitivity and specificity of the ABI and TBI were determined by color duplex sonography. Receiver operating characteristic (ROC) analysis was performed. RESULTS: A total of 119 participants were recruited (75 male and 44 female). The sensitivity for PAD was highest for the TBI (71%; ABI, 45%), and the specificity was highest for the ABI (93%; TBI, 78%). Receiver operating characteristic analysis indicated that the TBI (ROC area, 0.77; P = .0001) had greater clinical efficacy for diagnosis of PAD than the ABI (ROC area, 0.65; P = .005). CONCLUSIONS: In specific populations, the TBI may have greater clinical efficacy than the ABI for diagnosis of PAD.
- Subject
- ankle-brachial index; peripheral arterial disease; sensitivity; specificity; toe-brachial index; vascular ultrasound
- Identifier
- http://hdl.handle.net/1959.13/1327488
- Identifier
- uon:25677
- Identifier
- ISSN:1550-9613
- Rights
- This is the peer reviewed version of the following article: Tehan, P., Bray, A., Keech, R., Rounsley, R., Carruthers, A. and Chuter, V. H. (2015), Sensitivity and Specificity of the Toe-Brachial Index for Detecting Peripheral Arterial Disease. Journal of Ultrasound in Medicine, 34: 1737–1743, which has been published in final form at http://dx.doi.org/10.7863/ultra.15.14.09071. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
- Language
- eng
- Full Text
- Reviewed
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